Everything about The Subfornical Organ totally explained
The
subfornical organ, situated on the ventral surface of the
fornix, at the
foramen of Monro, is one of the
circumventricular organs of the
brain.
Relations with other circumventricular organs
Other circumventricular organs are the
area postrema in the brainstem and the
organum vasculosum of the lamina terminalis (OVLT).
The OVLT and the SFO are both strongly interconnected with the
nucleus medianus, and together these three structures comprise the so called "AV3V" region - the region anterior and ventral to the
third ventricle. The AV3V region is very important in the regulation of
fluid and electrolyte balance, by controlling
thirst,
sodium excretion,
blood volume regulation, and
vasopressin secretion.
The SFO is outside the
blood-brain barrier, and so neurons in this region can respond to factors that are present in the systemic circulation.
Receptors
Some neurons in the SFO are
osmoreceptors, being sensitive to the
osmotic pressure of the blood. These neurons project to the
supraoptic nucleus and
paraventricular nucleus to regulate the activity of
vasopressin-secreting neurons. These neurons also project to the
nucleus medianus (also called the median preoptic nucleus) which is involved in controlling
thirst. Thus, The subfornical organ is involved in
fluid balance.
In addition, neurons in the SFO have receptors for many hormones that circulate in the blood but which don't cross the blood-brain barrier, including
angiotensin,
atrial natriuretic hormone,
endothelin and
relaxin.
Further Information
Get more info on 'Subfornical Organ'.
|
External Link Exchanges
Do you know how hard it is to get a link from a large encyclopaedia? Well we're different and will prove it. To get a link from us just add the following HTML to your site on a relevant page:
<a href="http://subfornical_organ.totallyexplained.com">Subfornical organ Totally Explained</a>
Then simply click through this link from your web page. Our crawlers will verify your link, extract the title of your web page and instantly add a link back to it. If you like you can remove the words Totally Explained and embed the link in article text.
As long as your link remains in place, we'll keep our link to you right here. Please play fair - our crawlers are watching. Your site must be closely related to this one's topic. Any kind of spamming, dubious practises or removing the link will result in your link from us being dropped and, potentially, your whole site being banned. |
